Description
Letrozole is approved to be used alone or with other drugs to treat:
- Breast cancer in postmenopausal women who have any of the following types of breast cancer–
- Early-stage, hormone receptor–positive (HR+) breast cancer that has been treated.
- Early-stage breast cancer that has been treated with tamoxifen citrate for at least 5 years.
- Breast cancer that is locally advanced or has metastasized (spread to other parts of the body) and is HR+. It is used as the first treatment.
- Breast cancer that is locally advanced or has metastasized and it is not known whether the cancer is HR+ or hormone receptor negative (HR-). It is used as the first treatment.
- Breast cancer that has gotten worse after antiestrogen therapy. It is used as the second treatment.
- Letrozole is also being studied in the treatment of other types of cancer.
A drug used to treat certain types of breast cancer in postmenopausal women. It is also being studied in the treatment of other types of cancer. Letrozole lowers the amount of estrogen made by the body. This may stop the growth of cancer cells that need estrogen to grow. Letrozole is a type of aromatase inhibitor. Also called Femara.